Step 1: Open Control Panel and go to “Folder Options”.
Step 2: The user has to choose the “View” tab and then check the box that is labeled “Do not cache thumbnails”.
Step 3: Now the user must click on “OK” for saving the settings.There is another method for disabling the creation of Thumbs.db
Step 1: Go to Start menu and click on Run.
Step 2: When the Run dialog opens, the user has to type “cmd” and then hit the Enter key.
Step 3: In the command prompt window that appears, the user must type “REG ADD"HKCR\Software\Microsoft\Windows\CurrentVersion\Explorer\Advanced" /v DisableThumbnailCache /t REG_DWORD /d 1 /f”.
Step 4: Now the user must hit Enter for disabling creation of Thumbs.db file successfully.In case there are problems, contact an online technical support provider for assistance.
If you are using the Windows XP operating system, then know that you have the liberty to toggle the Control Panel according to your wish. The Control Panel of Windows XP has two views, one is the classic view and the other is category view. The classic view of the Control Panel lists all the items in the same window, whereas the category view groups the items together according to their functionality or behavior and lists them. You can do the toggling by following some simple steps, however if there are issues you may contact the 
